Age-specific salivary immunoglobulin A response to Streptococcus mutans GbpB.

نویسندگان

  • Ruchele D Nogueira
  • Alessandra C Alves
  • William F King
  • Reginaldo B Gonçalves
  • José F Höfling
  • Daniel J Smith
  • Renata O Mattos-Graner
چکیده

In a follow-up study of children infected with Streptococcus mutans at an early age (children previously shown to respond poorly to S. mutans GbpB), there was a delay in their immune response, rather than a complete inability to respond to this antigen. Epitopes in the N-terminal third of GbpB were identified as targets for naturally induced immunoglobulin A antibody in children at an early age.

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عنوان ژورنال:
  • Clinical and vaccine immunology : CVI

دوره 14 6  شماره 

صفحات  -

تاریخ انتشار 2007